Buy Portrazza (necitumumab) From Cancerdrugs247.com
What is Portrazza (necitumumab) for?
Portrazza (necitumumab) is a monoclonal antibody indicated for the treatment of people with metastatic squamous non-small cell lung cancer in combination with gemcitabine and cisplatin — two widely approved medicines1,2.
How does Portrazza (necitumumab) work?
The active substance in Portrazza, necitumumab, is an epidermal growth factor receptor (EGFR) antagonist1, a type of protein designed to recognise and attach to EGFR on the surface of the cancer cells. EGFR normally controls the growth and division of cells, but in cancer cells EGFR is often overactive, causing the cells to divide uncontrollably. By attaching to and blocking EGFR, necitumumab helps to reduce the growth and spread of the cancer2.
Where has Portrazza (necitumumab) been approved?
Portrazza (necitumumab) was approved for the first line treatment of advanced squamous NSCLC by:
- Food and Drug Administration (FDA), USA, November 11, 20154
- European Medical Agency (EMA), European Union, March 4, 20162.
Please note that this medicine may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.
How is Portrazza (necitumumab) taken?
The standard dosage is:
- 800 mg as an intravenous infusion over 60 minutes on Days 1 and 8 of each 3-week cycle1,3
Administered in addition to gemcitabine and cisplatin-based chemotherapy for up to 6 cycles of treatment followed by necitumumab as a single agent in patients whose disease has not progressed, until disease progression or unacceptable toxicity3
Administer necitumumab prior to gemcitabine and cisplatin infusion1
Warning: Closely monitor serum electrolytes: cardiopulmonary arrest and/or sudden death occurred in 3% of patients treated with Portrazza in combination with gemcitabine and cisplatin.
Complete information about Portrazza (necitumumab) dosage and administration can be found in the official prescribing information listed in our resources section1,3.
Note: Please consult with your treating doctor for personalised dosing.
Are there any known side effects of Portrazza (necitumumab)?
Common side effects
The most common side effects listed in the prescribing information include1,3:
- skin reactions (rash)
- venous thromboembolic events.
Serious side effects
The serious side effects listed in the prescribing information include1,3:
- skin reactions
- venous thromboembolic events: cardiopulmonary arrest and/or sudden death occurred in 3% of patients
- hypomagnesemia occurred in 83% of patients and was severe in 20%.
Use in a specific population
Portrazza (necitumumab) can be fatal for a fetus, it is advised to avoid pregnancies and breast feeding1,3.
Follow the following prescription medicine precautions :
|Portrazza may be harmful in pregnancy and there is a potential risk of miscarriage or carrying a child with birth defects if you or your partner becomes pregnant during this time. Take proper medical help in case you are pregnant, may be pregnant or planning to become pregnant in the near future.|
|This medicine is not indicated for use in women. It is not known if Portrazza is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Portrazza, a decision should be made to either discontinue nursing, or discontinue the drug taking into account the importance of the drug to the mother.|
|Your health care professional may recommend blood tests to see how your body is working. Blood tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatments are working.|
|Before taking Portrazza, tell your doctor and pharmacist if you are allergic to Portrazza, any other medications, or any of the ingredients in Portrazza injection. This medicine is not recommended for use in patients with a known allergy to Portrazza.|
|If you take Portrazza, you must stop drinking alcohol. This is one of the ways to prevent this disease from getting worse. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.|
|If you use other prescription drugs or over the counter products at the same time, the effects of Portrazza may change. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your pharmacist can help you prevent or manage drug interactions.|
|Missing a dose of Portrazza can upset your treatment plan. If you do miss one of your doses, take it as soon as you remember, unless it’s almost time to take your next dose. In this case, you should just skip the missed dose. Don’t take a double dose to “make up” for the one you missed. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.|
|Do not take Portrazza the use by (expiry) date printed on the pack. Do not take it if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.|
|During your treatment with Portrazza, it is very important for your doctor to know about your medical history if you have Kidney problems, liver problems, HIV, triglycerides, diabetes or other health problems.|
What are the storage instructions for Portrazza ?
Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.
- Store Portrazza at 20°C to 25°C (68°F to 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).
- Store it in a cool, dry place, protected from light and refrigerated when necessary. Improper storage can affect the effectiveness and shelf life of your medicine.
- Consider storing your medications separately from your other family members. You can put them on a different shelf, or in a different cabinet or drawer.
- If you’re driving, you may want to have certain medicines at hand, but don’t store them in the glove compartment, where they could be damaged from the heat, cold, or rain outside or from the car’s heater or air conditioner.
- Always remember to store your medication out of sight and reach of children and pets, to prevent accidental ingestion.
cancerdrugs247.com is one of the leading suppliers of Portrazza and has won the trust of thousands of customers by delivering Portrazza cancer medicine at the lowest price globally. If you want to buy Portrazza, place your order online and get them delivered at your doorsteps within the specified time-frame.
We Ship in – USA, UK, China, Canada, Russia, Australia, UAE, Singapore, Philippines, Bulgaria, Hungary, Italy, Kenya, Nigeria, Saudi Arabia, Taiwan, Zimbabwe, Malaysia, Spain, Hong Kong and many other countries.
In order to legally purchase this medicine from Cancerdrugs247.com , you’ll require a prescription from your Registered Medical Practitioner.
The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.